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Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (C-Avi-6His) Biotinylated

Recombinant Human Tumor-associated Calcium Signal Transducer 2/TROP-2 (C-Avi-6His) Biotinylated

Item no.	PKSH034007-100
Manufacturer	Elabscience
Amount	100 ug
Quantity options	100 ug 20 ug
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized Powder
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	HEK293 cells
Conjugate/Tag	HIS, Avi
Purity	> 95 % as determined by reducing SDS-PAGE.
Sequence	His27-Thr274
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Cell surface glycoprotein Trop-2, Membrane component chromosome 1 surface marker 1, TACSTD2, TROP2, Tumor-associated calcium signal transducer 2
Shipping Condition	Cool pack
Available
Manufacturer - Category	Recombinant Proteins / Others
Manufacturer - Conjugate / Tag	C-Avi-His
Shipping Temperature	This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight	30.5 kDa
Observed Molecular Weight	40-60 kDa
Background	Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.
Abbreviation	TROP-2
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Reconstitution	Please refer to the printed manual for detailed information.
Formulation	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Activity	Immobilized Biotinylated Human TROP-2-Avi-His at 1μg/ml (100 μl/well) can bind Anti-Human TROP-2 mAb.The ED50 of Anti-Human TROP-2 mAb s 4.19 ng/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

PKSH034007-100-datasheet.pdf

PKSH034007-100-safety-datasheet.pdf