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SARS-CoV-2 (COVID-19) UK variant (B.1.1.7) S RBD (N501Y) Recombinant Protein

SARS-CoV-2 (COVID-19) UK variant (B.1.1.7) S RBD (N501Y) Recombinant Protein

Manufacturer	ProSci
Category	Infectious Diseases Viral Infections Coronavirus (COVID-19) Peptides & Proteins Recombinant Proteins SDS-PAGE
Type	Proteins Recombinant
Specific against	other
Format	Lyophilized
Applications	WB, ELISA
Amount	0.1 mg
Item no.	PRS-11-069-0.1mg
eClass 6.1	34160400
eClass 9.0	42020190
Available
Applications	SDS-PAGE
Applications	SDS-PAGE
Buffer	20mM PB (pH 7.4). 5 % trehalose is added as protectant before lyophilization.
Storage Conditions	Store in working aliquots at -20˚ C. Avoid freeze/thaw cycles.
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC Endotoxin level is less than 1EU per ug by the LAL method.
Background	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
1St Image Caption3	Immobilized SARS-CoV S protein RBD (N501Y), His Tag at 0.5 ug/ml (100ug/Well) on the plate. Dose response curve for Human ACE2, Fc Tag with the EC50 of 12.7 ng/ml determined by ELISA.
3Rd Image Caption	Human ACE2 captured in protein A chip, can bind SARS-CoV S protein RBD (N501Y), His Tag with an affinity constant of 1.74nM as determined in SPR assap (Biacore T200).
4Th Image Caption	SARS-COV2 S protein RBD (N501Y) on Tris-Bis PAGE under reduced condition. The purity os great than 95%.
Accession #	QHD43416.1
Fusion Tag	His-Avi
Sequence	Arg319 - Phe541 (N501Y)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 6/6/2024