Comparison

Activin A Recombinant Protein

Item no. PRS-40-213-0.002mg
Manufacturer ProSci
Amount 0.002 mg
Quantity options 0.002 mg 0.01 mg
Category
Type Proteins Recombinant
Format Lyophilized
Specific against other
Purity Greater than 97% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
NCBI SMAD2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias JV18,MADH2,MADR2,JV18-1,hMAD-2,hSMAD2,Mothers against decapentaplegic homolog 2,MAD homolog 2
Shipping Condition Room temperature
Available
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
The lyophilized Activin A recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Activin A is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Activin A recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Biological Activity
The ED50 was determined by its ability to inhibit the proliferation of murine MPC - 11 cells is ≤ 2.0 ng/mL, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Background
Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Human Activin A is a 26.0 kDa disulfide-linked homodimer of two β A chains, each containing 116 amino acid residues.
By Type
Cancer, Cell Cycle, Signal Transduction
Protein Gi #
51173730
NCBI Official Name
SMAD family member 2
NCBI Organism
Homo sapiens
Disclaimer
This product is for research use only.
Manufacturer - Species
Human
By Species
Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.002 mg
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close