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IL-33 Recombinant Protein

IL-33 Recombinant Protein

Item no.	PRS-40-273-0.01mg
Manufacturer	ProSci
Amount	0.01 mg
Quantity options	0.002 mg 0.01 mg
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Glial Cell Markers Neurodegeneration Markers;Research Area Neuroinflammation
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	Greater than 98% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence	MSITGISPIT EYLASLSTYN DQSITFALED ESYEIYVEDL KKDEKKDKVL LSYYESQHPS NESGDGVDGK MLMVTLSPTK DFWLHANNKE HSVELHKCEK PLPDQAFFVL HNMHSNCVSF ECKTDPGVFI GVKDNHLALI KVDSSENLCT ENILFKLSET
NCBI	IL33
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DVS27, IL1F11, NF-HEV, NFEHEV, C9orf26, NFHEV, Interleukin-33, Interleukin-1 family member 11, IL-33
Available
Storage Conditions	The lyophilized IL-33 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-33 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IL-33 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Biological Activity	The ED50 was determined by the dose - dependent stimulation of the proliferation of murine D10S cells is ≤ 0.05 ng/mL, corresponding to a specific activity of ≥ 2 x 107units/mg.
Background	Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant human IL-33 is a 17.9 kDa protein containing 159 amino acid residues.
Protein Gi #	313851030
NCBI Official Name	interleukin 33
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.01 mg

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Delivery expected until 11/6/2025

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