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TSLP Recombinant Protein

TSLP Recombinant Protein

Item no.	PRS-40-294-0.002mg
Manufacturer	ProSci
Amount	0.002 mg
Quantity options	0.002 mg 0.01 mg
Category	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Neural Transcription Factors Peptides & Proteins Recombinant Proteins By Organ Heart & Blood Cancer Testicular & Prostate Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	Greater than 98% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence	MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKE MFAMKTKAAL AIWCPGYSET QINATQAMKK RRKRKVTTNK CLEQVSQLQG L WRRFNRPL LKQQ
NCBI	TSLP
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Thymic stromal lymphopoietin
Available
Storage Conditions	The lyophilized TSLP recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TSLP is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing TSLP recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Background	TSLP is a hemopoietic protein that is expressed in the heart, liver and prostate. TSLP overlaps biological activities with IL-7 and binds with the heterodimeric receptor complex consisting of the IL-7R alpha chain (IL-7Rα ) and the TSLP-specific chain (TSLPR). Like IL-7, TSLP induces phosphorylation of STAT3 and STAT5, but uses kinases other than the JAKs for activation. TSLP prohibited apoptosis and stimulated growth of the human acute myeloid leukemia (AML)-derived cell line MUTZ3. It induces the release of T cell-attracting chemokines TARC and MDC from monocytes and activates CD11c(+) dendritic cells (DCs). TSLP activated DCs primed naïve T cells to produce the proallergic cytokines (IL-4, IL-5, IL-13, TNFα) while down-regulating IL-10 and IFN-γ suggesting a role in initiating allergic inflammation. Recombinant human TSLP is a 15.0 kDa protein consisting of 132 amino acid residues.
Protein Gi #	14719428
NCBI Official Name	thymic stromal lymphopoietin
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.002 mg

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Delivery expected until 10/2/2025

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