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Soluble TRAIL Receptor-1 Recombinant Protein

Soluble TRAIL Receptor-1 Recombinant Protein

Item no.	PRS-40-309-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Quantity options	0.01 mg 0.05 mg
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	Greater than 98% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence	MSGTGAAAAT PSKVWGSSAG RIEPRGGGRG ALPTSMGQHG PSARARAGRA PGPRPAREAS PRLRVHKTFK FVVVGVLLQV VPSSAATIKL HDQSIGTQQW EHSPLGELCP PGSHRSERPG ACNRCTEGVG YTNASQQLFA CLPCTACKSD EEERSPCTTT RNTACQCKPG TFRNDNSAEM CRKCSTGCPR GMVKVKDCTP WSDIECVHKE SGNGHN
NCBI	TNFRSF10A
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DR4,APO2,CD261,TRAILR1,TRAILR-1,DR4,Tumor necrosis factor receptor superfamily member 10A,Death receptor 4,TRAIL receptor 1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	The lyophilized Soluble TRAIL Receptor-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Soluble TRAIL Receptor-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Soluble TRAIL Receptor-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Biological Activity	Biological activity was determined by its inhibitory effect of IL - 8 production in human PBMC by human sTRAIL/Apo2L. 95% inhibition (100 ng/mL of s TRAIL/Apo2L) was reached using a concentration of 100 ng/mL of sTRAIL Receptor - 1.
Background	TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain, " which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane anchored or soluble TRAIL/Apo2L. Recombinant human soluble TRAIL Receptor-1/DR4 is a 22.7 kDa protein (215 amino acid residues) consisting of the TNFR homologous, cysteine rich portion of the extracellular domain.
By Type	Apoptosis, Cancer, Homeostasis, Immunology, Signal Transduction
Protein Gi #	259906438
NCBI Official Name	tumor necrosis factor receptor superfamily, member 10a
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 12/4/2025

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