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TWEAK Receptor Recombinant Protein

TWEAK Receptor Recombinant Protein

Item no.	PRS-40-312-0.005mg
Manufacturer	ProSci
Amount	0.005 mg
Quantity options	0.005 mg 0.025 mg
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis By Organ Colorectal Cancer
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	Greater than 98% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence	EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP
NCBI	TNFRSF12A
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	FN14,CD266,TWEAKR,FN14,Tumor necrosis factor receptor superfamily member 12A,Fibroblast growth factor-inducible immediate-early response protein 14,FGF-inducible 14
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	The lyophilized TWEAK Receptor recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TWEAK Receptor is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TWEAK Receptor recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Biological Activity	Biological activity was determined by its ability to inhibit TWEAK - induced weak cell death of HT29 cells. The expected ED50 for this effect is 1.0 - 3.0 μ g/mL.
Background	TWEAKR belongs to the TNF family of transmembrane proteins and contains a cytoplasmic "death domain", which can activated the cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein.
By Type	Apoptosis
Protein Gi #	7706186
NCBI Official Name	tumor necrosis factor receptor superfamily, member 12A
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.005 mg

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Delivery expected until 12/4/2025

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