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LIGHT Recombinant Protein

LIGHT Recombinant Protein

Item no.	PRS-40-452-0.005mg
Manufacturer	ProSci
Amount	0.005 mg
Quantity options	0.005 mg 0.02 mg
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis
Type	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	Greater than 98% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence	MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV
NCBI	Tnfsf14
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LTg,HVEML,LIGHT,Ly113,HVEM-L,Light,Tumor necrosis factor ligand superfamily member 14
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	The lyophilized LIGHT recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing LIGHT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Background	LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβ R, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.
Protein Gi #	9507195
NCBI Official Name	tumor necrosis factor (ligand) superfamily, member 14
NCBI Organism	Mus musculus
Disclaimer	This product is for research use only.
Manufacturer - Species	Murine
By Species	Mouse

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.005 mg

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Delivery expected until 12/4/2025

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