Comparison

IL-10 Recombinant Protein

Item no. PRS-40-471-0.002mg
Manufacturer ProSci
Amount 0.002 mg
Quantity options 0.002 mg 0.01 mg
Category
Type Proteins Recombinant
Format Lyophilized
Specific against other
Purity Greater than 98% by SDS-PAGE gel and HPLC analyses.<br><br>Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Sequence SKGHSIKGDN NCTHFPVSQT HMLRELRAAF SQVKTFFQKK DQLDNIVLTD SLLQDFKGYL GCQALSEMIK FYLVEVMPQA ENHGPEIKEH LNSLGEKLKT LWIQLRRCHR FLPCENKSKA VEQVKNDFNK LQDKGVYKAM NEFDIFINCI EAYVTLKMKN
NCBI Il10
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL10X,Il-10,Interleukin-10,Cytokine synthesis inhibitory factor,IL-10
Shipping Condition Room temperature
Available
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
The lyophilized IL-10 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IL-10 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IL-10 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Biological Activity
The ED50 was determined by the dose - dependent inhibition of antigen - specific T cell proliferation is less than 10 ng/mL.
Background
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα . Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant rat IL-10 is an 18.7 kDa protein of 160 amino acid residues.
By Type
Chemokines & Cytokines, Immunology
Protein Gi #
148747382
NCBI Official Name
interleukin 10
NCBI Organism
Rattus norvegicus
Disclaimer
This product is for research use only.
Manufacturer - Species
Rat
By Species
Rat

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.002 mg
Available: In stock
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