Comparison

TPO Recombinant Protein

Item no. PRS-40-585-0.002mg
Manufacturer ProSci
Amount 0.002 mg
Quantity options 0.002 mg 0.01 mg
Category
Type Proteins Recombinant
Format Lyophilized
Specific against other
Purity Greater than 98% by SDS-PAGE gel and HPLC analyses.
Sequence SPVPPACDPR LLNKLLRDSY LLHSRLSQCP DVNPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPPQGRTTA HKDPSALFLS LQQLLRGKVR FLLLVEGPAL CVRRTLPTTA VPSRTSQLLT LNKF
NCBI Thpo
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Thrombopoietin
Shipping Condition Room temperature
Available
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
The lyophilized TPO recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TPO stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TPO recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Biological Activity
Biological activity was determined by its ability to stimulate the proliferation of human MO7e cells. The expected B>ED50 is ≤ 0.2 ng/mL, corresponding to a specific activity of ≥ 5 x 106 units/mg. Endotoxin level is less than 0.1 ng per μ g (1EU/μ g).
Background
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant rat TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
Protein Gi #
13592113
NCBI Official Name
thrombopoietin
NCBI Organism
Rattus norvegicus
Disclaimer
This product is for research use only.
Manufacturer - Species
Rat
By Species
Rat

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.002 mg
Available: In stock
available

Delivery expected until 12/4/2025 

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