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Growth Hormone Receptor Recombinant Protein

Growth Hormone Receptor Recombinant Protein

Item no.	PRS-96-351-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Aging & Neurological Disorders Peptides & Proteins Recombinant Proteins Western Blot By Organ Skin Cancer Lymphatic System Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB
Specific against	other
Conjugate/Tag	Fc
Purity	>95% as determined by SDS-PAGE.
Sequence	Ala 27 - Tyr 264
Citations	Duquesnoy P., et al., 1994, EMBO J. 13:1386-1395. Urbanek M., et al., 1993, J. Biol. Chem. 268:19025-19032.
NCBI	GHR
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	GHR,GHBP,GH receptor
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Manufacturer - Conjugate / Tag	C-Fc Tag
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	54.3 kDa
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized Human GH, Tag Free at 2μ g/mL (100 μ L/well) can bind Human GHR, Fc Tag with a linear range of 0.19-3.1 ng/mL.
Background	Growth hormone receptor (GHR) is also known as somatotropin receptor, growth hormone-binding protein (GHBR), which belongs to the type I cytokine receptor family or Type 1 subfamily. GHR contains one fibronectin type-III domain. GHR / GHBR is expressed in various tissues with high expression in liver and skeletal muscle. The soluble form (GHBP) is produced by phorbol ester-promoted proteolytic cleavage at the cell surface (shedding) by ADAM17/TACE. GHR is receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
By Type	Growth Factors
Buffer	50 mM tris, 100 mM glycine, pH7.5
Application Note	This recombinant protein can be used for WB. For research use only.
NCBI Official Name	growth hormone receptor
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 2/5/2026

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