Item no. |
PVG-C5253-100ug |
Manufacturer |
ACROBiosystems
|
Amount |
100 ug |
Quantity options |
100 ug
1 mg
|
Category |
|
Type |
Proteins Recombinant |
Format |
Powder |
Specific against |
Monkey (Cynomolgus, Simian) |
Host |
HEK293 |
Isotype |
IgG2a |
Conjugate/Tag |
Unconjugated, C-mFc |
Purity |
95% |
NCBI |
XP_005549281.1 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC138297,MGC2463,PVRIG,CD112 receptor |
Shipping condition |
Room temperature |
Available |
|
Specificity |
Cynomolgus |
Manufacturer - Category |
Protein / Immune Checkpoint Proteins |
Manufacturer - Conjugate / Tag |
Unconjugated, C-mFc(mIgG2a) |
Manufacturer - Species |
Cynomolgus |
Shipping Temperature |
RT |
Storage Conditions |
-20°C |
Molecular Weight |
40.7 kDa |
Description |
Cynomolgus PVRIG, Mouse IgG2a Fc Tag (PVG-C5253) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # A0A2K5WVV8-1). |
Background |
Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. |
Molecule |
PVRIG |
Exp Region |
Thr 41 - Asp 171 |
Characteristics |
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 40.7 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
0.1 EU per μg |
Buffer |
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5 |
Stability |
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution.For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Protectant |
trehalose |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.