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Cynomolgus PVRIG Protein, Mouse IgG2a Fc Tag (MALS verified) European Partner

Item no. PVG-C5253-100ug
Manufacturer ACROBiosystems
Amount 100 ug
Quantity options 100 ug 1 mg
Category
Type Proteins Recombinant
Format Powder
Specific against Monkey (Cynomolgus, Simian)
Host HEK293
Isotype IgG2a
Conjugate/Tag Unconjugated, C-mFc
Purity 95%
NCBI XP_005549281.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC138297,MGC2463,PVRIG,CD112 receptor
Shipping condition Room temperature
Available
Specificity Cynomolgus
Manufacturer - Category
Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag
Unconjugated, C-mFc(mIgG2a)
Manufacturer - Species
Cynomolgus
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
40.7 kDa
Description
Cynomolgus PVRIG, Mouse IgG2a Fc Tag (PVG-C5253) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # A0A2K5WVV8-1).
Background
Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Molecule
PVRIG
Exp Region
Thr 41 - Asp 171
Characteristics
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 40.7 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
0.1 EU per μg
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution.For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
available

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