Item no. |
S10-H5127-1mg |
Manufacturer |
ACROBiosystems
|
Amount |
1 mg |
Quantity options |
100 ug
1 mg
|
Category |
|
Type |
Proteins Recombinant |
Format |
Solid |
Specific against |
Human (Homo sapiens) |
Host |
E.coli |
Conjugate/Tag |
Unconjugated, HIS |
Purity |
95% |
Citations |
(1) Harder T., et al., 1992,Gene. 113(2):269-74. (2) Choudhary C., et al., 2009, Science 325:834-840. (3) Rety S., et al., 1999, Nat. Struct. Biol. 6:89-95. |
NCBI |
AAH15973 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
S100A10,p11,p10,ANX2LG,CAL1L,CLP11 |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Category |
Protein / Other Recombinant Proteins |
Manufacturer - Conjugate / Tag |
C-6xHis, Unconjugated |
Shipping Temperature |
RT |
Storage Conditions |
-20°C |
Molecular Weight |
12.0 kDa |
Manufacturer - Format |
Powder |
Description |
Human S100A10, His Tag (S10-H5127) is expressed from E. coli cells. It contains AA Met 1 - Lys 97 (Accession # AAH15973). |
Background |
S100 calcium-binding protein A10 (S100A10), a member of the S100 family of proteins containing two EF-hand calcium-binding motifs, is also known as protein S100-A10, calpactin I light chain, cellular ligand of annexin II, p10 protein and p11, which can be found as a free monomer, a homodimer, or a heterotetramer composed of a p11 dimer complex with two molecules of annexin II. S100A10 is an integral part of cellular structural scaffolding that interacts with plasma membrane proteins through its association with annexin II. S100A10 also works together with cytosolic and peripheral membrane-associated proteins such as AHNAK in the development of the intracellular membrane. Furthermore, S100A10 has been implicated in the transportation of proteins involved in mood regulation, nociception, and cell polarization. Complexed with the annexin II, S100A10 binds receptor and channel proteins and guides them to the cell surface, resulting in increased membrane localization and consequent magnified functional expression of these proteins. |
Molecule |
S100A10 |
Exp Region |
Met 1 - Lys 97 |
Characteristics |
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.0 kDa. The protein migrates as 14 kDa under reducing (R) condition (SDS-PAGE). |
Endotoxin |
1.0 EU per μg |
Buffer |
50 mM Tris, 150 mM NaCl, pH8.0 |
Stability |
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Protectant |
trehalose |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.