Comparison

HCoV-229E S1 protein, His Tag European Partner

Item no. SIN-V52H4-1mg
Manufacturer ACROBiosystems
Amount 1 mg
Quantity options 100 ug 1 mg
Category
Type Proteins Recombinant
Format Solid
Specific against Coronavirus
Host HEK293
Conjugate/Tag Unconjugated, HIS
Purity 90%
Citations (1) Wan Y, et al. J Virol. 2020. pii: JVI.00127-20.
(2) Benvenuto D, et al. J Med Virol. 2020.
(3) Chang CY, et al. AMB Express. 2020. 10(1):20.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1,COVID-19
Shipping Condition Room temperature
Available
Specificity HCoV-229E
Manufacturer - Category
Protein / Viral Proteins
Manufacturer - Conjugate / Tag
C-10xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
58.8 kDa
Manufacturer - Format
Powder
Description
HCoV-229E S1 protein, His Tag (SIN-V52H4) is expressed from human 293 cells (HEK293). It contains AA Cys 16 - Ala 536 (Accession # P15423-1).
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Molecule
Spike S1
Exp Region
Cys 16 - Ala 536
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.8 kDa. The protein migrates as 70-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH 7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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