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Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free

Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free

Item no.	TAU-H5115-500ug
Manufacturer	ACROBiosystems
Amount	500 ug
Quantity options	100 ug 500 ug x 2 500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	Unconjugated
Purity	90%
Dry ice	Yes
NCBI	NP_005901.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU
Shipping Condition	Dry ice
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	Native, Unconjugated
Shipping Temperature	Dry ice
Storage Conditions	-70°C
Molecular Weight	45.8 kDa
Manufacturer - Format	Liquid
Description	Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
Background	Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
Molecule	Tau
Exp Region	Met 1 - Leu 441
Characteristics	This protein carries no "tag". The protein has a calculated MW of 45.8 kDa.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● The product should be stored at -70°C or room temperature for short storage. Do not store fibrils on ice or at 4°C ● The unsonicated fibril is validated to be stable after storage at -70°C for 1 year under sterile conditions ● The sonicated fibril should be stored at -70°C for not more than 8 weeks.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TAU-H5115-500ug-datasheet.pdf

TAU-H5115-500ug-safety-datasheet.pdf