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Mouse Transferrin R2 Protein, mouse IgG1 Fc Tag, low endotoxin

Mouse Transferrin R2 Protein, mouse IgG1 Fc Tag, low endotoxin

Item no.	TF2-M5269-50ug
Manufacturer	ACROBiosystems
Amount	50 ug
Quantity options	200 ug x 5 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293
Isotype	IgG1
Conjugate/Tag	Unconjugated, N-mFc
Purity	95%
Citations	(1) Kawabata H., et al., 2001, Blood 98:1949-1954.
NCBI	NP_056614.3
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Transferrin R2,TFR2
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-mFc(mIgG1), Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	101.1 kDa
Manufacturer - Format	Powder
Description	Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
Background	Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
Molecule	Transferrin R2
Exp Region	Arg 103 - Phe 798
Characteristics	This protein carries a mouse IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 101.1 kDa. The protein migrates as 116 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.1 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TF2-M5269-50ug-datasheet.pdf

TF2-M5269-50ug-safety-datasheet.pdf