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Mouse anti-F3 (3A5-D6-D9-D4-F9) [+Biotin]

Mouse anti-F3 (3A5-D6-D9-D4-F9) [+Biotin]

Manufacturer	Raybiotech
Category	Oncology Antibodies ELISA Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody Monoclonal
Specific against	Human
Clone	Monoclonal
Format	Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1 x PBS to a final concentration of 1 mg/ml.
Applications	ELISA
Amount	50 ug
Host	Mouse
Item no.	130-10276B-50
eClass 6.1	32160702
eClass 9.0	42030590
Available
Target Name	F3
Accession Number	P13726
Conjugate/Tag/Label	Biotin
Application notes:	ELISA (recommended work dilution= 1:320, 000), Western Blotting (recommended work dilution= 1:1, 000-5, 000),
Product Description	F3 gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.
Immunogen	Immunogen was recombinant protein. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.

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