Anti-IL-5 Antibody

ELISA (dilution: 0.1, 0.2ug/ml), Flow Cytometry, Functional Assays, Western Blotting

Ambient temperature

Rabbit Anti-Human IL-5

Phosphate buffered saline

Purified IgG - lyophilized

Reconstitute with 0.1ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended. NB: For functional studies do not add azide.

This product is specific for human IL-5 (Interleukin-5), a disulphide-linked homodimer consisting of two 115 amino acid chains, which is homologous to mouse eosinophil differentiation factor (EDF) and is produced by mast cells, eosinophils and T cells. IL-5 is a lineage-specific cytokine involved in the development and stimulation of eosinophils, and has been linked with diseases involving abnormally high levels of eosinophils, including parasitic infections and allergic airways eosinophilia, the major pathological symptom of allergic asthma.

Antisera to human IL-5 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.