Anti-Lymphotactin / XCL1 Antibody

ELISA (dilution: 0.1, 0.2ug/ml), Functional Assays, Immunohistology - Paraffin, Western Blotting

Ambient temperature

Rabbit Anti-Human Lymphotactin / XCL1

Phosphate buffered saline

Purified IgG - lyophilized

Reconstitute with 0.1 ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended. NB: For functional studies do not use azide.

This product is specific for human Lymphotactin, otherwise known as XCL1, the only member of the C-chemokine family identified so far. Unlike other members of the chemokine superfamily, Lymphotactin uniquely acts as a chemoattractant for lymphocytes, but not monocytes or neutrophils, suggesting an important regulatory role in lymphocyte trafficking and inflammation. Lymphotactin, shown to signal through chemokine XC receptor 1 (XCR1), is detected at the highest level in the spleen and at low levels in the lungs, small intestine and colon, and is abundantly and selectively expressed by activated T cells, in particular CD8+ T cells, and is also produced by NK cells.

Antisera to human lymphotactin were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.