Comparison

Rabbit Anti-Human IGF1

Item no. DS-PB-02644
Manufacturer Raybiotech
Amount 0.1 mg
Category
Type Antibody
Format Purified
Specific against Human (Homo sapiens)
Host Hamster - Armenian
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products IGF1
Available
Specificity This product is specific for human IGF-I (Insulin-like Growth Factor I), a 70 amino acid secreted mitogenic polypeptide and member of the insulin gene family, produced primarily by the liver. IGF-I exhibits both autocrine and paracrine properties and has
Expiration
12 months from the date of shipment when stored properly.
Format
Purified IgG - lyophilized
Formulation
Phosphate buffered saline
Protein Name & Synonyms
IGF1
Concentration
IgG concentration 1.0mg/ml after reconstitution (lot specific)
Reconstitution
Reconstitute with 0.1ml distilled water. For long term storage the addition of 0.09% sodium azide is recommended. NB: For functional studies do not add azide.
Preservative
None present
Manufacturer - Specificity
This product is specific for human IGF-I (Insulin-like Growth Factor I), a 70 amino acid secreted mitogenic polypeptide and member of the insulin gene family, produced primarily by the liver. IGF-I exhibits both autocrine and paracrine properties and has a widespread effect on cells including those of the bone, cartilage, muscle, nerves, skin, liver and lungs, playing a key role in cell proliferation and growth, inhibition of apoptosis and linked with tumour cell growth.IGF-I signals through binding to the type 1 insulin-like growth factor receptor (IGF-1R) and also to the insulin receptor (IR), resulting in the activation of the AKT signalling pathway. Production of IGF-I is stimulated by growth hormone (GH) and can be hindered by GH insensitivity, deficiency in GH receptors or a malfunction in the post GH receptor signalling pathway.
Preparation
Antisera to human IGF-I were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen
Recombinant human IGF-I

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

 
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