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Rabbit anti-Adiponutrin (C-terminus) [+Biotin]

Rabbit anti-Adiponutrin (C-terminus) [+Biotin]

Manufacturer	Raybiotech
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies ELISA Enzymes Fatty Acid Catabolism Primary Antibodies
Type	Antibody
Specific against	Human
Isotype	IgG
Format	Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1x PBS to a final concentration of 1 mg/ml.
Applications	ELISA
Amount	50 ug
Host	Rabbit
Item no.	RB-08-0033B-50
Targets	PNPLA3
eClass 6.1	32160702
eClass 9.0	32160702
Available
Target Name	Adiponutrin (C-terminus)
Accession Number	NM_025225
Conjugate/Tag/Label	Biotin
Application notes:	ELISA (recommended work dilution= 1:10^6), Western Blotting (recommended work dilution= 1:1000-5000(at least))
Product Description	Adiponutrin, designated as ADPN is a 53 kDa member of the PNPLA family of phospholipase A2 enzymes. It also is called as PNPLA3, patatin-like phospholipase domain-containing protein 3. ADPN is expressed in white adipocytes. Very importantly, it is a predominantly liver-expressed transmembrane protein with phospholipase activity that is regulated by fasting and feeding. Recent genome-wide association studies identified PNPLA3 to be associated with hepatic fat content and liver function, thus pointing to a possible involvement in the hepatic lipoprotein metabolism. Investigation also demonstrated that adiponutrin could be involved in vesicular targeting and protein transport restricted to the adipocyte function.
Immunogen	Immunogen was a synthetic peptide derived from Human Adiponutrin. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.