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Zinc Protoporphyrin (Standard)

Zinc Protoporphyrin (Standard)

Item no.	HY-101193R-5mg
Manufacturer	MedChem Express
CASRN	15442-64-5
Amount	5 mg
Quantity options	1 ea 10 mg 1 mg 25 mg 5 mg
Category	Reagents & Chemicals Material Science Metal Compounds
Type	Chemicals
Specific against	other
Purity	97.80
Citations	[1]Park C, et al. Protective Effect of Phloroglucinol on Oxidative Stress-Induced DNA Damage and Apoptosisthrough Activation of the Nrf2/HO-1 Signaling Pathway in HaCaT Human Keratinocytes. Mar Drugs. 2019 Apr 13;17(4).\|[2]Mwangi MN, et al. Diagnostic utility of zinc protoporphyrin to detect iron deficiency in Kenyan pregnant women. BMC Med. 2014 Nov 26;12:229.\|[3]Nowis D, et al. Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice. BMC Cancer. 2008 Jul 11;8:197.
Smiles	OC(CCC1=C(C=C2[N]3=C4C(C)=C2CCC(O)=O)[N-]([Zn+2]35[N]6=C7C=C(C(C=C)=C8C)[N-]5C8=C4)C(C=C6C(C=C)=C7C)=C1C)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Zn(II)-protoporphyrin IX (Standard),ZnPP (Standard),Zinc Protoporphyrin-9 (Standard)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference Standards
Manufacturer - Category	Reference compound / Active compounds; Natural Products
Manufacturer - HS Code	H302, H315, H319, H335
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, sealed storage, away from light and moisture
Product Description	Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2[1]. Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration[2]. Zinc Protoporphyrin has anti-cancer activity[3].
Manufacturer - Research Area	Cancer; Metabolic Disease; Cardiovascular Disease
Manufacturer - Pathway	Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
UNSPSC Code	12352211
Precautionary	H302, H315, H319, H335

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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