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PRLX-93936

PRLX-93936

Item no.	HY-119264-1mg
Manufacturer	MedChem Express
CASRN	903499-49-0
Amount	1 mg
Quantity options	1 mg 5 mg
Category	Reagents & Chemicals Standards, Ladders & Markers
Type	Standard
Specific against	other
Citations	[1]Huang W, et al. Synthesis and evaluation of quinazolin-4-ones as hypoxia-inducible factor-1α inhibitors. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5239-43. [2]Voorhees P M, et al. An open-label, dose escalation, multi-center phase 1 study of PRLX 93936, an agent synthetically active against the activated ras pathway, in the treatment of relapsed or relapsed and refractory multiple myeloma[J]. Blood, 2014, 124(21): 2140.
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	HIF/HIF Prolyl-Hydroxylase; Ras
Shipping Temperature	Room temperature
Product Description	PRLX-93936 dihydrochloride (Compound 16) is a HIF-1α inhibitor with anticancer activity. PRLX-93936 can inhibit the activated Ras pathway and can be used in the study of relapsed or refractory multiple myeloma[1][2].
Manufacturer - Research Area	Cancer
Manufacturer - Pathway	GPCR/G Protein; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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