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Thalidomide-NH-CH2-COOH (TFA)

Thalidomide-NH-CH2-COOH (TFA)

Item no.	HY-131717A-10mg
Manufacturer	MedChem Express
CASRN	2377032-39-6
Amount	10 mg
Quantity options	1 ea 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Standards, Ladders & Markers
Type	Standard
Specific against	other
Citations	[1]Calla M Olson, et al. Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation. Nat Chem Biol. 2018 Feb;14(2):163-170.\|[2]Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation
Smiles	O=C(O)CNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(C(F)(F)F)O
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	E3 Ligase Ligand-Linker Conjugates
Shipping Temperature	Room temperature
Molecular Weight	445.30
Product Description	Thalidomide-NH-CH2-COOH TFA is a ligand-linker conjugate for the E3 ligase Cereblon (CRBN). Thalidomide-NH-CH2-COOH TFA can be conjugated to multi-targeted kinase inhibitors to transform them into selective degraders [1] [2] .
Manufacturer - Research Area	Cancer
Manufacturer - Pathway	PROTAC
Clinical information	No Development Reported

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Amount: 10 mg

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