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Desmethyl Sibutramine (hydrochloride) (Standard)

Desmethyl Sibutramine (hydrochloride) (Standard)

Item no.	HY-135615AR-10mg
Manufacturer	MedChem Express
CASRN	84467-94-7
Amount	10 mg
Quantity options	1 ea 100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Standards, Ladders & Markers Other Standards
Type	Standard
Specific against	other
Citations	[1]Talbot PS, et, al. Brain serotonin transporter occupancy by oral sibutramine dosed to steady state: a PET study using (11)C-DASB in healthy humans. Neuropsychopharmacology. 2010 Feb;35(3):741-51. \|[2]Luscombe GP, et, al. The contribution of metabolites to the rapid and potent down-regulation of rat cortical beta-adrenoceptors by the putative antidepressant sibutramine hydrochloride. Neuropharmacology. 1989 Feb;28(2):129-34.\|[3]Wang J, et, al. Analysis of six synthetic adulterants in herbal weight-reducing dietary supplements by LC electrospray ionization-MS. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2008 Jul;25(7):822-30.\|[4]Ponnuru VS, et, al. Quantification of sibutramine and its two metabolites in human plasma by LC-ESI-MS/MS and its application in a bioequivalence study. J Pharm Anal. 2012 Aug;2(4):249-257.
Smiles	ClC1=CC=C(C2(C(CC(C)C)NC)CCC2)C=C1.Cl
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Alias	N-Desmethylsibutramine (hydrochloride) (Standard)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference Standards
Manufacturer - Targets	Reference Standards; Serotonin Transporter
Shipping Temperature	Room temperature
Molecular Weight	302.28
Product Description	Desmethyl Sibutramine (hydrochloride) (Standard) is the analytical standard of Desmethyl Sibutramine (hydrochloride). This product is intended for research and analytical applications. Desmethyl Sibutramine hydrochloride, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine hydrochloride can be used in the research of obesity and appetite suppressant[1][2][3][4].
Manufacturer - Research Area	Metabolic Disease; Neurological Disease
Manufacturer - Pathway	Neuronal Signaling; Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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