MY-875

Item no.	HY-150761-10mM
Manufacturer	MedChem Express
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.44
Citations	[1]Jian Song, et al. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway. Eur J Med Chem. 2022 Jul 7;240:114583.
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Apoptosis; Microtubule/Tubulin
Shipping Temperature	Room Temperature
Product Description	MY-875 is a competitive microtubulin polymerization inhibitor with an IC50 value of 0.92 μM. MY-875 inhibits microtubulin polymerization by targeting colchicine binding sites and activates the Hippo pathway. MY-875 induces apoptosis and has anticancer activity[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 250 mg/mL
Manufacturer - Pathway	Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Clinical information	No Development Reported

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HY-150761-10mM-safety-datasheet.pdf