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Vormatrigine

Vormatrigine

Item no.	HY-159819-100mg
Manufacturer	MedChem Express
CASRN	2392951-18-5
Amount	100 mg
Quantity options	1 ea 100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Standards, Ladders & Markers
Type	Standard
Specific against	other
Purity	99.73
Citations	[1]Praxis Precision Medicines, Inc. Preparation of pyridin-3-yl substituted triazolopyrazines, triazolopyridazines, and triazolopyridines as ion channel modulators. World Intellectual Property Organization, WO2019232209 A1 2019-12-05 [2]Praxis Presentation of Epilepsy Program Advances Set for 2024 American Epilepsy Society Annual Meeting
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Sodium Channel
Shipping Temperature	Room Temperature
Molecular Weight	406.28
Product Description	Vormatrigine is an orally active sodium channel inhibitor with anti-epileptic activity. Vormatrigine has a specific inhibitory effect on overactive NaV channels in vitro and has a good inhibitory effect in the maximal electroconvulsive seizure (MES) model. Vormatrigine can be used to study human focal and generalized epilepsy[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO : 175 mg/mL (ultrasonic)
Manufacturer - Pathway	Membrane Transporter/Ion Channel
Clinical information	No Development Reported

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