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DBM-C5-VC-PAB-MMAE

DBM-C5-VC-PAB-MMAE

Item no.	HY-164088-1mg
Manufacturer	MedChem Express
CASRN	1644228-55-6
Amount	1 mg
Quantity options	10 mg 1 mg 5 mg
Category	Reagents & Chemicals Ligands & Crosslinkers Crosslinkers
Type	Crosslinkers
Specific against	other
Purity	99.45
Citations	[1]Feuillâtre O, et al., Impact of Maleimide Disubstitution on Chemical and Biological Characteristics of HER2 Antibody-Drug Conjugates. ACS Omega. 2020 Jan 17;5(3):1557-1565.
Smiles	O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN4C(C(Br)=C(C4=O)Br)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
ECLASS 10.1	32170205
ECLASS 11.0	32170205
UNSPSC	41105316
Shipping Condition	Cool pack
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Drug-Linker Conjugates for ADC; Microtubule/Tubulin
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	1474.42
Product Description	DBM-C5-VC-PAB-MMAE (Compound 3a) is a Drug-Linker conjugate for ADC. DBM-C5-VC-PAB-MMAE is composed of a linker C5-VC-PAB with a maleimide group DBM and an ADC toxin MMAE (HY-15162)[1].
Manufacturer - Research Area	Cancer
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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