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Maridebart cafraglutide

Maridebart cafraglutide

Item no.	HY-164535-10mg
Manufacturer	MedChem Express
CASRN	2887445-76-1
Amount	10 mg
Quantity options	1 ea 10 mg 1 mg 5 mg
Category	Reagents & Chemicals Ligands & Crosslinkers Crosslinkers
Type	Crosslinkers
Specific against	other
Citations	[1]Bloomgarden Z T. The 2023 WCIRDC: Obesity[J]. Journal of Diabetes, 2024, 16(4).\|[2]Véniant MM, et al. A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settings. Nat Metab. 2024 Feb;6(2):290-303.
Smiles	[Maridebart cafraglutide]
ECLASS 10.1	32170205
ECLASS 11.0	32170205
UNSPSC	41105316
Alias	AMG 133
Shipping Condition	Room temperature
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	GLP Receptor
Shipping Temperature	Room temperature
Molecular Weight	153, 514 (average)
Product Description	Maridebart cafraglutide (AMG 133) is an antibody-peptide conjugate acting as a GLP-1 receptor agonist and an antagonist of the GIP receptor. Maridebart cafraglutide reduces body weight and improve metabolic markers in male obese mice and cynomolgus monkeys. Maridebart cafraglutide is promising for research of obesity[1][2].
Manufacturer - Research Area	Metabolic Disease
Manufacturer - Pathway	GPCR/G Protein
Clinical information	Phase 1

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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