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VcMMAE-Deruxtecan

VcMMAE-Deruxtecan

Item no.	HY-164835
Manufacturer	MedChem Express
CASRN	2760408-75-9
Amount	1 ea
Quantity options	1 ea 10 mg 1 mg 5 mg
Category	Reagents & Chemicals Ligands & Crosslinkers Crosslinkers
Type	Crosslinkers
Specific against	other
Purity	98.10
Smiles	CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C3=CC=CC=C3)=O)([H])CCC2)=O)C)=O)=O)=O)C=C1)=O)=O)NC(C(NC(CCCCCN4C(C=CC4=O)=O)=O)CC(C=C5)=CC=C5OCC(NCC(NCC(N[C@@H](CC6=CC=CC=C6)C(NCC(NCOCC(N[C@@H]7C8=C9C(C(N%10C9)=CC([C@](O)(C(OC%11)=O)CC)=C%11C%10=O)=NC%12=CC(F)=C(C)C(CC7)=C%128)=O)=O)=O)=O)=O)=O)=O
ECLASS 10.1	32170205
ECLASS 11.0	32170205
UNSPSC	41105316
Alias	SMP-54418
Shipping Condition	Room temperature
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Drug-Linker Conjugates for ADC; Microtubule/Tubulin; Topoisomerase
Shipping Temperature	Room temperature
Storage Conditions	-20°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	2360.67
Product Description	VcMMAE-Deruxtecan is a Drug-Linker Conjugates for ADC, which is composed of a linker and a toxic molecule MMAE (HY-15162) (Microtubule inhibitor) and Exatecan (HY-13631) (DNA topoisomerase I inhibitor). VcMMAE-Deruxtecan can be used for ADC synthesis.
Manufacturer - Research Area	Cancer
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Isoform	Dual payloads; Topo I
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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