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Melatonin (standard)

Melatonin (standard)

Item no.	HY-B0075R-250mg
Manufacturer	MedChem Express
CASRN	73-31-4
Amount	250 mg
Quantity options	1 ea 100 mg 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Standards, Ladders & Markers Other Standards
Type	Standard
Specific against	other
Citations	[3]Rahim I, et al. Melatonin administration to wild-type mice and non-treated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis. J Pineal Res. 2017 Mar 31\|[4]Bu LJ, et al. Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation. World J Gastroenterol. 2017 Feb 14;23(6):986-998.\|[5]Zhi Chen, et al. Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress. J Ovarian Res. 2019 May 10;12(1):43.\|[1]Kilic U, et al. Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice. Redox Biol. 2017 Apr 5;12:657-665\|[2]Hu C, et al. Neuroprotective effect of melatonin on soluble Aβ1-42-induced cortical neurodegeneration via Reelin-Dab1 signaling pathway. Neurol Res. 2017 Apr 7:1-1
Smiles	CC(NCCC1=CNC2=C1C=C(OC)C=C2)=O
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Alias	N-Acetyl-5-methoxytryptamine (standard),Melatonin
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference Standards
Manufacturer - Targets	Apoptosis; Autophagy; Endogenous Metabolite; Melatonin Receptor; Mitophagy; Reference Standards
Shipping Temperature	Room temperature
Molecular Weight	232.283
Product Description	Melatonin (Standard) is the analytical standard of Melatonin. This product is intended for research and analytical applications. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5].
Manufacturer - Research Area	Cancer; Inflammation/Immunology; Neurological Disease
Manufacturer - Pathway	Apoptosis; Autophagy; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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