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Hyodeoxycholic acid (Standard)

Hyodeoxycholic acid (Standard)

Item no.	HY-N0169R-25mg
Manufacturer	MedChem Express
CASRN	83-49-8
Amount	25 mg
Quantity options	1 ea 100 mg 10 mg 25 mg 50 mg
Category	Reagents & Chemicals Standards, Ladders & Markers Other Standards
Type	Standard
Specific against	other
Citations	[1]Sato H, et al. Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies. J Med Chem. 2008 Mar 27;51(6):1831-41.\|[2]Shih DM, et al. Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR-knockout mice. FASEB J. 2013 Sep;27(9):3805-17.
Smiles	C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])C[C@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Alias	HDCA (Standard)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference Standards
Manufacturer - Targets	Endogenous Metabolite; G protein-coupled Bile Acid Receptor 1; Reference Standards
Shipping Temperature	Room temperature
Molecular Weight	392.57
Product Description	Hyodeoxycholic acid (Standard) is the analytical standard of Hyodeoxycholic acid. This product is intended for research and analytical applications. Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells.
Manufacturer - Research Area	Metabolic Disease
Manufacturer - Pathway	GPCR/G Protein; Metabolic Enzyme/Protease; Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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