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Fraxinellone (Standard)

Fraxinellone (Standard)

Item no.	HY-N0242R-5mg
Manufacturer	MedChem Express
CASRN	28808-62-0
Amount	5 mg
Quantity options	1 ea 100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Other Chemicals
Type	Standard
Specific against	other
Citations	[1]Xing Y, et al. Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death-ligand 1 expression by reducing hypoxia-inducible factor-1α and STAT3. Pharmacol Res. 2018 Sep;135:166-180.
Smiles	O=C1O[C@@H](C2=COC=C2)[C@]3(C)CCCC(C)=C31
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference Standards
Manufacturer - Targets	HIF/HIF Prolyl-Hydroxylase; PD-1/PD-L1; STAT
Shipping Temperature	Room temperature
Molecular Weight	232.28
Product Description	Fraxinellone (Standard) is the analytical standard of Fraxinellone. This product is intended for research and analytical applications. Fraxinellone is isolated from the root bark of the Rutaceae plant, Dictamnus dasycarpus. Fraxinellone is a PD-L1 inhibitor and inhibits HIF-1α protein synthesis without affecting HIF-1α protein degradation. Fraxinellone has the potential to be a valuable candidate for cancer treatment by targeting PD-L1 [1] .
Manufacturer - Research Area	Cancer; Inflammation/Immunology
Manufacturer - Pathway	Immunology/Inflammation; JAK/STAT Signaling; Metabolic Enzyme/Protease; Stem Cell/Wnt

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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