Comparison

ICA-105665 European Partner

Item no. TMO-T11606-50mg
Manufacturer TargetMol
CASRN 2694728-63-5
Amount 50 mg
Quantity options 100 mg 200 mg 25 mg 500 mg 50 mg
Category
Type Molecules
Specific against other
Smiles N(C(CC1=CC=C(F)C=C1)=O)N2C(=NC=3C(C2=O)=CC=C(F)C3)C4CC4
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias PF-04895162
Shipping Condition Cool pack
Available
Manufacturer - Targets
Others
Storage Conditions
-20
Molecular Weight
355.34
Description
ICA-105665 (PF-04895162) is a potent and orally active opener of neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects [1][2][3][4].
Pathways
Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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