NNK

Item no.	TMO-T20533-10mM
Manufacturer	TargetMol
CASRN	64091-91-4
Amount	1 mL x 10 mM (in DMSO)
Quantity options	1000 mg 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	CN(CCCC(=O)c1cccnc1)N=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Nicotine-derived nitrosamine ketone
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Lipoxygenase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	207.23
Description	NNK is a nicotinic nitrosylated derivative. It activates ERK1/2 and PKCα, and activates Bcl2 phosphorylation at Ser70, as well as c-Myc at Thr58 and Ser62.It can be used to construct mouse models of lung cancer, as well as to induce proliferation and survival of human lung cancer cells.
Pathways	Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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