Artesunate-d4

Blue Ice

388, 45

Supplied as a white solid

Labeled derivative of Artemisinin. Antimalarial.

Synonyms:
Butanedioic Acid Mono(3R, 5aS, 6R, 8aS, 9R, 10R, 12R, 12aR)-decahydro-3, 6, 9-trimethyl-3, 12-epoxy-12H-pyrano[4, 3-j]-1, 2-benzodioxepin-10-yl] Ester-d4; Artesunic Acid-d4

CAS No:
1316753-15-7

Molecular Formula:
C₁₉H₂₄D₄O₈

Molecular Weight:
388.45

Appearance:
Supplied as a white solid

Melting Point:
130-132°C

Solubility:
Chloroform (Slightly), Methanol (Slightly)

Method for Determining Identity:
Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis

TLC Conditions:
SiO2; Dichloromethane: Methanol: 9:1; Visualized with AMCS and UV; Single spot, Rf=0.60

Elemental Analysis:
Calculated: %C: 58.75, %H: 7.27

Normalized Intensity:
d0=0.27%, d1=0.45%; d2=1.08%; d3=3.96%, d4=8.91%; d5=94.24%

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Store under inert atmosphere.