Alsterpaullone

RT

293, 3

Supplied as a yellow to brown powder.

Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor. Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM). GSK-3beta (glycogen synthase kinase-3beta) inhibitor. Apoptosis inhibitor. Apoptosis inducer. Angiogenesis inhibitor.

Synonyms:
9-Nitro-7, 12-dihydroindolo-[3, 2-d][1]benzazepin-6(5H)-one

CAS Number:
237430-03-4

Molecular Weight:
293.3

Molecular Formula:
C16H11N3O3

Solubility:
DMSO; insoluble in water or 100% ethanol.

Appearance:
Supplied as a yellow to brown powder.

Purity:
≥98% (NMR)

Storage and Stability:
Store at 4°C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.