L-NMMA monoacetate

Blue Ice

248, 3

Supplied as a white to off-white solid.

Endothelium-derived relaxing factor inhibitor. Inhibits the generation of NO from arginine. Competitive, irreversible non-selective inhibitor of all three NOS I, II, and III isoforms (eNOS, iNOS and nNOS). Inhibits the synthesis of nitric oxide (NO) in a dose-dependent and enantiospecific fashion. Useful tool to study the role and the effects of NO in cardiovascular and gastrointestinal disorders, hypertension, diabetes, septic shock, inflammation, infection, stroke and neurodegenerative disorders.

Synonyms:
NG-Monomethyl-L-arginine . monoacetate

CAS Number:
53308-83-1

Molecular Weight:
248.3

Molecular Formula:
C7H16N4O2•CH3COOH

Solubility:
Water, ethanol, methanol or DMSO

Appearance:
Supplied as a white to off-white solid.

Purity:
≥99% (TLC)

Storage and Stability:
Store at 4°C. Keep cool and dry. Stable for 12 months after receipt when stored at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.