Fmoc-L-tert-Leucine

Biochemicals / Biochem-Amino Acids, Fmoc

4°C

Highly Purified

Fmoc-L-tert-Leucine is an amide that is used for the treatment of prostate cancer. Fmoc-L-tert-Leucine has been shown to be effective in treating resistant prostate cancer cells in vivo, and it has been shown to inhibit the growth of prostate cancer cells in vitro. This drug also has a diagnostic effect on prostate cancer cells. The uptake of this drug by prostate cancer cells is dependent on the presence of caspase-9, which may be due to its ability to inhibit apoptosis.

Synonyms:
Fmoc-L-Tle-OH; Fmoc-L-alpha-t-butylglycine; Fmoc-α-t-butylglycine, N-α-Fmoc-L-α-t.-butyl-glycine; NPC 15573; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3, 3-dimethylbutanoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-methyl-L-valine

CAS No:
132684-60-7

Molecular Formula:
C21H23NO4

Molecular Weight:
353.41

Purity:
≥97% (HPLC)

Appearance:
White to off-white solid

Melting Point:
124-127°C (lit)

1H NMR Spectrum:
Conforms to structure

Water (KF):
As Reported

Optical Rotation (c=1, Methanol):
As Reported

Storage and Stability:
Powder may be stored at 4°C. Stable for 6 months after receipt