Ganglioside GM1, Bovine, Sodium Salt (Monosialoganglioside GM1)

Blue Ice

1568, 8

Supplied as a white to off-white lyophilized powder.

A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera toxin. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system. It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorylation and synaptic function.

Synonyms:
Monosialoanglioside GM1,  sodium salt (Bovine brain)

Nomenclature:
[II3Neu5AcGgOse4Cer][b-Gal-(1-3)-b-GalNAc-(1-4)-[a-Neu5Ac-(2-3)]-b-Gal(1-4)-b-Glc-(1-1')-Cer]

CAS No:
37758-47-7

Molecular Formula:
C73H131N3O31

Molecular Weight:
1546.82

Purity (HPLC):
≥95%

Appearance:
White to off-white powder

FT-IR Spectrum:
Conforms to reference spectrum

Storage and Stability:
Store at -20ºC. Product is stable for 6 months from time of receipt.