Comparison

NSC-23766 3HCl

Item no. V0012-10mg
Manufacturer InvivoChem LLC
CASRN 1177865-17-6
Amount 10 mg
Quantity options 100 mg 250 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V0012CAS #:1177865-17-6Purity >=98%

Description: NSC23766 3HCl, the salt form of NSC23766, is a novel and potent inhibitor of Rac GTPase, it targets the Rac activation by guanine nucleotide exchange factors (GEFs) with an IC50 of ca.50 uM in a cell-free assay; NSC23766 does not inhibit Cdc42 or RhoA, the closely related targets.

References: Proc Natl Acad Sci U S A. 2004 May 18; 101(20):7618-23; J Biol Chem. 2005 Nov 11; 280(45):37516-25.

Related CAS: 733767-34-5 (free base)

Molecular Weight (MW)
530.96
Formula
C24H35N7.3HCl
CAS No.
1177865-17-6 (HCl)
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 100 mg/mL (188.3 mM)
Water: < 1 mg/mL
Ethanol: 100 mg/mL (188.3 mM)
Other info
Chemical Name: N6-(2-((5-(diethylamino)pentan-2-yl)amino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4, 6-diamine trihydrochloride
InChi Key: CPUHORIUXPQCHW-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22; ; ; /h10-11, 13-16H, 6-9, 12H2, 1-5H3, (H2, 25, 26)(H2, 27, 28, 29, 30); 3*1H
SMILES Code: NC1=CC(C)=NC2=CC=C(NC3=NC(NC(CCCN(CC)CC)C)=NC(C)=C3)C=C12.[H]Cl.[H]Cl.[H]Cl
Synonyms
NSC-23766 3HCl; NSC-23766 3Hydrochloride; NSC23766; NSC-23766; NSC 23766

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
available

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