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JNJ-26854165 (Serdemetan)

JNJ-26854165 (Serdemetan)

Item no.	V0013-10mg
Manufacturer	InvivoChem LLC
CASRN	881202-45-5
Amount	10 mg
Quantity options	100 mg 1 mg 250 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0013CAS #:881202-45-5Purity >=98% Description: Serdemetan (formerly JNJ26854165; JNJ-26854165; JNJ 26854165), originally developed as an activator of p53, is now considered to be a novel, potent and orally bioactive antagonist of Human Double Minute-2 (HDM-2) ubiquitin ligase with antitumor activities. It also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Reference: Pediatr Blood Cancer. 2012 Aug; 59(2):329-32.
Molecular Weight (MW)	328.41
Formula	C21H20N4
CAS No.	881202-45-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 66 mg/mL (200.96 mM)
	Water:< 1 mg/mL (slightly soluble or insoluble)
	Ethanol: 2 mg/mL (6.08 mM)
Solubility (In vivo)	1% DMSO+30% polyethylene glycol+1% Tween 80: 30 mg/mL
Synonyms	JNJ26854165; JNJ-26854165; JNJ 26854165

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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