AZ31

Item no.	TMO-T19671-10mg
Manufacturer	TargetMol
CASRN	2088113-98-6
Amount	10 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	N([C@@H](C)C1CCOCC1)C=2C3=C(N=CC2C(N)=O)C=CC(=C3)C=4C=CC(COC)=NC4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AZ 31,AZ-31
Shipping Condition	Cool pack
Available
Manufacturer - Targets	ATM/ATR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	420.5
Description	AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.
Pathways	PI3K/Akt/mTOR signaling\|\|\|DNA Damage/DNA Repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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