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Birinapant (TL32711)

Birinapant (TL32711)

Item no.	V0051-25mg
Manufacturer	InvivoChem LLC
CASRN	1260251-31-7
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0051CAS #:1260251-31-7Purity >=98% Description: Birinapant (TL32711; TL-32711; TL 32711) is a novel and potent bivalent peptidomimeticof SMAC (second mitochondrial-derived activator of caspases) andinhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins. It has potential anticancer activity. Birinapant is a SMAC mimetic antagonist, mostly to cIAP1 with a Kd of < 1 nM in a cell-free assay, and is less potent to XIAP. Description:peptidomimeticof SMAC (second mitochondrial-derived activator of caspases) andinhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins. It has potential anticancer activity. References: Breast Cancer Res Treat. 2013 Jan; 137(2):359-71. References:
Molecular Weight (MW)	806.94
Formula	C42H56F2N8O6
CAS No.	1260251-31-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (123.9 mM)
	Water:< 1 mg/mL (slightly soluble or insoluble)
	Ethanol: 55 mg/mL (68.1 mM)
Solubility (In vivo)	15% Captisol: 15mg/mL
Synonym	TL32711; TL-32711; TL 32711; SMAC mimetic; Birinapant
Chemical Name	(2S, 2'S)-N, N'-((2S, 2'S)-((3S, 3'S, 5R, 5'R)-5, 5'-((6, 6'-difluoro-1H, 1'H-[2, 2'-biindole]-3, 3'-diyl)bis(methylene))bis(3-hydroxypyrrolidine-5, 1-diyl))bis(1-oxobutane-2, 1-diyl))bis(2-(methylamino)propanamide)

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Amount: 25 mg

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Delivery expected until 9/4/2025

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