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Pixantrone dimaleate (BBR-2778)

Pixantrone dimaleate (BBR-2778)

Item no.	V0067-50mg
Manufacturer	InvivoChem LLC
CASRN	144675-97-8
Amount	50 mg
Quantity options	100 mg 1 g 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0067CAS #:144675-97-8Purity >=98% Description: Pixantrone dimaleate, the dimaleate salt of Pixantrone (formerly known as BBR 2778) and an aza-anthracenedione analog, is a weak topoisomerase II inhibitor and DNA intercalator with anticancer activity with little cardiotoxicity. It acts by forming stable DNA adducts via alkylation with specificity for DNA hypermethylated sites. Description: References: Invest New Drugs. 2007 Jun; 25(3):187-95. References: Related CAS: 144510-96-3 (free base); 175989-38-5 (HCl)
Molecular Weight (MW)	557.51
Formula	C17H19N5O2.2C4H4O4
CAS No.	144675-97-8 (dimaleate)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 100 mg/mL
	Water: > 100 mg/mL
	Ethanol:< 1 mg/mL
Chemical Name	6, 9-bis((2-aminoethyl)amino)benzo[g]isoquinoline-5, 10-dione dimaleate
Synonyms	BBR-2778 dimaleate; BBR2778 dimaleate; BBR 2778
SMILES Code	O=C(C1=C(NCCN)C=CC(NCCN)=C12)C3=C(C=NC=C3)C2=O.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O

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