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Omipalisib (GSK2126458, GSK458)

Omipalisib (GSK2126458, GSK458)

Item no.	V0121-500mg
Manufacturer	InvivoChem LLC
CASRN	1086062-66-9
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0121CAS #:1086062-66-9Purity >=98% Description: Omipalisib (also called GSK-2126458, GSK-458), a pyridylsulfonamide analog, is a potent, highly selective and orally bioavailable small-molecule inhibitor of phosphatidylinositol 3-kinase (PI3K) p110alpha/beta/delta/gamma with potential anticancer activity. It is a dual PI3K/mToR Inhibitor that also inhibits mTORC1/2 with Ki values of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Omipalisib is a new investigational PI3K/mToR Inhibitor developed by GSK-Glaxo SmithKline and is currently undergoing clinical trials for cancer treatment. Description: Description: Omipalisib (also called GSK-2126458, GSK-458), a pyridylsulfonamide analog, is a potent, highly selective and orally bioavailable small-molecule inhibitor of phosphatidylinositol 3-kinase (PI3K) p110alpha/beta/delta/gamma with potential anticancer activity. It is a dual PI3K/mToR Inhibitor that also inhibits mTORC1/2 with Ki values of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Omipalisib is a new investigational PI3K/mToR Inhibitor developed by GSK-Glaxo SmithKline and is currently undergoing clinical trials for cancer treatment.pyridylsulfonamide analog, phosphatidylinositol 3-kinase (PI3K) OmipalisibPI3K/mToR Inhibitor References: Mol Cancer Ther. 2012 Apr; 11(4):909-20; ACS Med Chem Lett. 2010 Jan 19; 1(1):39-43. References: References:

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Amount: 500 mg

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Delivery expected until 10/2/2025

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