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AS-252424

AS-252424

Item no.	V0130-100mg
Manufacturer	InvivoChem LLC
CASRN	900515-16-4
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Sarcoma Cell Biology Cell Status Cytoskeleton Proliferation Reagents & Chemicals Intermediate filaments Molecules By Organ Bladder Cancer Breast Cancer
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0130CAS #:900515-16-4Purity >=98% Description: AS-252424 is a novel, potent, orally bioactive and selective PI3Kgamma inhibitor with potential anticancer activity. It inhibits PI3Kgamma with an IC50 of 30 nM in a cell-free assay and showed 30-fold selectivity for PI3Kgamma over PI3Kalpha, as well as low inhibitory activity against PI3Kdelta/beta. In Capan 1 and HPAF (pancreatic cancer cell lines), AS52424 specifically inhibited the cell proliferation. Description:Description: AS-252424 is a novel, potent, orally bioactive and selective PI3Kgamma inhibitor with potential anticancer activity. It inhibits PI3Kgamma with an IC50 of 30 nM in a cell-free assay and showed 30-fold selectivity for PI3Kgamma over PI3Kalpha, as well as low inhibitory activity against PI3Kdelta/beta. In Capan 1 and HPAF (pancreatic cancer cell lines), AS52424 specifically inhibited the cell proliferation.PI3Kgamma References:J Med Chem. 2006 Jun 29; 49(13):3857-71; Clin Cancer Res. 2010 Oct 15; 16(20):4928-37. References:References:

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 10/2/2025

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