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CH5132799

CH5132799

Item no.	V0138-250mg
Manufacturer	InvivoChem LLC
CASRN	1007207-67-1
Amount	250 mg
Quantity options	100 mg 10 mg 25 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0138CAS #:1007207-67-1Purity >=98% Description: CH5132799 is a novel and potent class I PI3K (phosphoinositide 3-kinase) inhibitor with potential anticancer activity. It inhibits class I PI3Ks, in particular, PI3Kalpha with an IC50 of 14 nM, and is less potent against PI3Kbetadeltagamma, while being sensitive in PIK3CA mutated cell lines. CH5132799 shows inhibitory effects against class I PI3K with IC50 values of 0.014uM, 0.12uM, 0.5uM and 0.036uM against PI3Kalpha, PI3Kbeta, PI3Kdelta and PI3Kgamma, respectively. Description:Description: CH5132799 is a novel and potent class I PI3K (phosphoinositide 3-kinase) inhibitor with potential anticancer activity. It inhibits class I PI3Ks, in particular, PI3Kalpha with an IC50 of 14 nM, and is less potent against PI3Kbetadeltagamma, while being sensitive in PIK3CA mutated cell lines. CH5132799 shows inhibitory effects against class I PI3K with IC50 values of 0.014uM, 0.12uM, 0.5uM and 0.036uM against PI3Kalpha, PI3Kbeta, PI3Kdelta and PI3Kgamma, respectively. References: Bioorg Med Chem Lett. 2011 Mar 15; 21(6):1767-72. References: References:
Molecular Weight (MW)	377.42
Formula	C15H19N7O3S
CAS No.	1007207-67-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 12 mg/mL (31.79 mM)
	Water:< 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	1% DMSO+30% polyethylene glycol+1% Tween 80: 30mg/mL
Synonyms/Chemical Name	CH5132799; CH-5132799; CH 5132799; PA-799; PA799; PA-799; 5-(7-methylsulfonyl-2-morpholin-4-yl-5, 6-dihydropyrrolo[2, 3-d]pyrimidin-4-yl)pyrimidin-2-amine

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 10/2/2025

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