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BIO-acetoxime (GSK-3 Inhibitor X; BIA)

BIO-acetoxime (GSK-3 Inhibitor X; BIA)

Item no.	V0228-10mg
Manufacturer	InvivoChem LLC
CASRN	667463-85-6
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Cardiovascular Research Ischemia & Reperfusion Injury Hypertension Reagents & Chemicals Arrhythmias Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0228CAS #:667463-85-6Purity >=98% Description: BIO-acetoxime (also known as GSK-3 Inhibitor X; BIA), a synthetic derivative of a compound from the Mediterranean mollusk Hexaplex trunculus, is a novel, potent and selective dual inhibitor of GSK3alpha/beta (glycogen synthase kinase-3) with potential anti-infection and anticonvulsant as well as anticancer effects. It inhibits GSK3alpha/beta with IC50s of 10 nM, and displayed > 240-fold selectivity for GSK over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B. Description: Description: BIO-acetoxime (also known as GSK-3 Inhibitor X; BIA), a synthetic derivative of a compound from the Mediterranean mollusk Hexaplex trunculus, is a novel, potent and selective dual inhibitor of GSK3alpha/beta (glycogen synthase kinase-3) with potential anti-infection and anticonvulsant as well as anticancer effects. It inhibits GSK3alpha/beta with IC50s of 10 nM, and displayed > 240-fold selectivity for GSK over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B. a synthetic derivative of a compound from the Mediterranean mollusk Hexaplex trunculus, anticonvulsant as well as anticancer effects. It anticonvulsant as well as anticancer effects. It anticancer GSK3alpha/beta GSK References:J Med Chem. 2004; 47(4):935-46; Mol Cell Biol. 2015; 35(17):3029-43; Mol Cancer Ther. 2014; 13(2):454-67. References:References:

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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Delivery expected until 10/2/2025

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