Amlodipine Besylate (Norvasc)

Description: Amlodipine (formerly UK-48340; Norvasc; used as as besylate, mesylate or maleate salts) is a selective and long-acting CCB-calcium channel blocker that belongs to the dihydropyridine (DHP) class. It is a anti-hypertensive medication used to lower blood pressure and prevent chest pain. Amlodipine causes a dose-dependent increase in nitrite production. Amlodipine also increases nitrite production in large coronary arteries and in aorta. Amlodipine is attributed to distinct membrane physico-chemical interactions.

References: J Mol Cell Cardiol. 1999 Jan; 31(1):275-81; J Hypertens. 1998 Apr; 16(4):457-66.

Related CAS #: 88150-42-9 (free base); 111470-99-6 (besylate); 246852-09-5 (HBr); 246852-07-3 (HCl); 246852-12-0 (mesylate); 440358-84-9 (mesylate hydrate); 88150-47-4 (maleate);

UK 48340; Cordarene; UK-48340; UK48340; Amlodipine besylate; Cardiorex;